
Keywords: فاکتور نکروز تومور; OPN; osteopontin; LCH; Langerhans cell histiocytosis; MS; multisystem; SS; single system; iDC; immature dendritic cell; Th; T helper; OCs; osteoclasts; JLSG; the Japan LCH Study Group; MS+; multisystem disease with liver, spleen and/or hematopoietic syste