
Investigating the contribution of CYP2J2 to ritonavir metabolism in vitro and in vivo
Keywords: درون تنی یا درونجانداری; CYP2J2; CYP2D6; CYP3A4; Time dependent inhibition; Ritonavir; In vivo; SimcypAUC, area under the plasma concentration–time curve; CYP, cytochrome P450 monooxygenase; EM, extensive metabolizer; IM, intermediate metabolizer; HLM, human liver microsomes; PM,