دانلود مقالات ISI درباره هدایت سیگنال + ترجمه فارسی

Emerging concepts in the regulation of the EGF receptor and other receptor tyrosine kinases

Keywords: هدایت سیگنال; receptor tyrosine kinases; epidermal growth factor receptor; signal transduction; allostery

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Roles for TNF-receptor associated factor 3 (TRAF3) in lymphocyte functions

Keywords: هدایت سیگنال; TRAF; B lymphocyte; T lymphocyte; Signal transduction; Lymphocyte activation

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Prior TLR5 induction in human T cells results in a transient potentiation of subsequent TCR-induced cytokine production

Keywords: هدایت سیگنال; APBTs; activated peripheral blood T cells; APC; antigen presenting cells; IFN-γ; interferon-γ; PAM; PAM3CSK4; Toll-like receptor 5; T cell receptor; T cells; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

Gax inhibits perivascular preadipocyte biofunction mediated by IGF-1 induced FAK/Pyk2 and ERK2 cooperative pathways

Keywords: هدایت سیگنال; Gax; IGF-1; Perivascular adipocyte; Signal transduction; Cell function;

دانلود رایگان متن کامل مقاله ISI 10 صفحه سال انتشار : 2014 سفارش ترجمه

The intricate interplay between RNA viruses and NF-κB

Keywords: هدایت سیگنال; ss; single-stranded; ds; double-stranded; HTLV; human T cell leukemia virus; SARS; severe acute respiratory syndrome; IAVs; influenza A viruses; IFN; interferon; IRF3; interferon regulatory factor 3; NF-κB; nuclear factor κB; TLRs; toll-like receptors;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Activating Mutations in PTPN3 Promote Cholangiocarcinoma Cell Proliferation and Migration and Are Associated With Tumor Recurrence in Patients

Keywords: هدایت سیگنال; Liver Cancer; Carcinogenesis; Signal Transduction; Phosphorylation; CI; confidence interval; HR; hazard ratio; ICC; intrahepatic cholangiocarcinoma; indel; insertion or deletion; mRNA; messenger RNA; PTP; protein tyrosine phosphatase; TTR; time to recurre

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

The immunomodulator AS101 suppresses production of inflammatory cytokines and ameliorates the pathogenesis of experimental autoimmune encephalomyelitis

Keywords: هدایت سیگنال; AS101; trichloro(dioxoethylene-O,O′) tellurate; EAE; experimental autoimmune encephalomyelitis; MOG; myelin oligodendrocyte glycoprotein; Inflammation; GM-CSF; IL-17; Signal transduction; Th17 cells; Stat3;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Deletion of SIRT1 From Hepatocytes in Mice Disrupts Lipin-1 Signaling and Aggravates Alcoholic Fatty Liver

Keywords: هدایت سیگنال; Alcoholic Fatty Liver; Lipid Metabolism; Inflammation; Signal Transduction; AH; alcoholic hepatitis; ALD; alcoholic liver disease; mRNA; messenger RNA; NFATc4; nuclear factor of activated T cells c4; PGC; peroxisome proliferator-activated receptor co-fact

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

β-Arrestins regulate human cardiac fibroblast transformation and collagen synthesis in adverse ventricular remodeling

Keywords: هدایت سیگنال; Heart failure; Receptors; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Molecular and cellular pharmacologyInvolvement of endogenous transforming growth factor-α in signal transduction pathway for interleukin-1β-induced hepatocyte proliferation

Keywords: هدایت سیگنال; DNA synthesis; Proliferation (cultured hepatocytes); Interleukin-1β; Transforming growth factor-α; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Phenotypic screen quantifying differential regulation of cardiac myocyte hypertrophy identifies CITED4 regulation of myocyte elongation

Keywords: هدایت سیگنال; Cardiac hypertrophy; Phenotypic screen; Cardiac myocytes; Signal transduction; CTGF; CITED4;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Adaptive Remodelling by FliN in the Bacterial Rotary Motor

Keywords: هدایت سیگنال; CW, clockwise; CCW, counterclockwise; TIRF, total internal reflection fluorescence; FRAP, fluorescence recovery after photobleaching; BFP, back focal planeEscherichia coli; bacterial motility; signal transduction; sensory adaptation; protein subunit excha

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Phosphorylated SHIP2 on Y1135 localizes at focal adhesions and at the mitotic spindle in cancer cell lines

Keywords: هدایت سیگنال; bpV(phen); potassium bisperoxo(1,10-phenanthroline)oxovanadate (V); EGF; epidermal growth factor; FBS; fetal bovine serum; FGF; fibroblast growth factor; GIST; gastrointestinal stromal tumor; IF; immunofluorescence; NHS; normal horse serum; PDGFRA; Alpha-

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

ERK/Egr-1 signaling pathway is involved in CysLT2 receptor-mediated IL-8 production in HEK293 cells

Keywords: هدایت سیگنال; Cysteinyl leukotriene receptor 2; Signal transduction; Interleukin-8; Extracellular signal-regulated kinase; Early growth response-1

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Cellular behavior as a dynamic field for exploring bone bioengineering: A closer look at cell–biomaterial interface

Keywords: هدایت سیگنال; Bone; Bioengineering; Osteoblast; Signal transduction; Cell behavior; Biomaterials; Scaffolds; Regenerative medicine; Dentistry

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Whole genome transcriptome analysis of rice seedling reveals alterations in Ca2+ ion signaling and homeostasis in response to Ca2+ deficiency

Keywords: هدایت سیگنال; Ca2+ deficiency; Starvation; Gene expression; Transcriptome analysis; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 11 صفحه سال انتشار : 2014 سفارش ترجمه

Protein kinase inhibitor SU6668 attenuates positive regulation of Gli proteins in cancer and multipotent progenitor cells

Keywords: هدایت سیگنال; AP; alkaline phosphatase; ASCs; adipose tissue derived stromal cells; GliACT; transcriptional activator form of Gli proteins; GliFL; full-length Gli proteins; Ptch; patched; RNAi; RNA interference; Shh; Sonic Hedgehog; Smo; Smoothened; shRNA; short hairpi

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Context-dependent signal integration by the GLI code: The oncogenic load, pathways, modifiers and implications for cancer therapy

Keywords: هدایت سیگنال; GLI transcription factors; Hedgehog-GLI signaling; Cancer; Development; Signal transduction; Signaling integration; Oncogenes; Stem cells;

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Mechanisms and targets of the modulatory action of S-nitrosoglutathione (GSNO) on inflammatory cytokines expression

Keywords: هدایت سیگنال; S-nitrosoglutathione; S-nitrosothiols; Nitric oxide; Inflammation; Inflammatory cytokines; Signal transduction

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Regulation of contractile signaling and matrix remodeling by T-cadherin in vascular smooth muscle cells: Constitutive and insulin-dependent effects

Keywords: هدایت سیگنال; E; empty vector control transductant; EC; endothelial cell; ECM; extracellular matrix; ED; endothelial dysfunction; Ins; insulin; IRS-1; insulin receptor substrate-1; MLC20; myosin light chain 20; MLCK; myosin light chain kinase; MLCP; myosin light chain

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

BDNF impairment is associated with age-related changes in the inner retina and exacerbates experimental glaucoma

Keywords: هدایت سیگنال; BDNF; brain derived neurotrophic factor; TrkB; tropomyosin related kinase B receptor; APP; amyloid precursor protein; ONH; optic nerve head; GCL; ganglion cell layer; H&E; haematoxylin and eosin; RGC; retinal ganglion cells; IOP; intraocular pressure; PI3

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Synthesis and biological evaluation of imidazo[1,2-a]pyrimidines and imidazo[1,2-a]pyridines as new inhibitors of the Wnt/β-catenin signaling

Keywords: هدایت سیگنال; Wnt signaling; β-catenin; Signal transduction; Colorectal cancer; Imidazo[1,2-a]pyrimidines; Imidazo[1,2-a]pyridinesAPC, Adenomatous Polyposis Coli; CBP, Cyclic AMP response element-Binding Protein; DAPI, 4′,6-diamidino-2-phenylindole; GFP, Green Fluoresc

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

Activation of Pattern Recognition Receptors Up-Regulates Metallothioneins, Thereby Increasing Intracellular Accumulation of Zinc, Autophagy, and Bacterial Clearance by Macrophages

Keywords: هدایت سیگنال; Innate Immunity; Inflammatory Bowel Disease; Signal Transduction; Intestinal InflammationBMM, bone marrow-derived macrophages; CD, Crohn’s disease; CFU, colony forming units; DSS, dextran sodium sulfate; GAPDH, glyceraldehyde-3-phosphate dehydrogenase; IL

دانلود رایگان متن کامل مقاله ISI 12 صفحه سال انتشار : 2014 سفارش ترجمه

The role of ABA and MAPK signaling pathways in plant abiotic stress responses

Keywords: هدایت سیگنال; Abscisic acid; Abiotic stress; MAP kinases; Signal transduction; ABA; Mitogen-activated protein kinases;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Targeted deletion of ERK2 in cardiomyocytes attenuates hypertrophic response but provokes pathological stress induced cardiac dysfunction

Keywords: هدایت سیگنال; Cardiac hypertrophy; Apoptosis; Interstitial fibrosis; Signal transduction; Genetically modified mice;

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

In vivo cross-linking combined with mass spectrometry analysis reveals receptor-like kinases and Ca2 + signalling proteins as putative interaction partners of pollen plasma membrane H+ ATPases

Keywords: هدایت سیگنال; Ab; antibody; CAM; calmodulin; CDPK; Ca2 +-dependent protein kinase; CBLs; calcineurin B-like Ca2 + sensor protein; CML; calmodulin-like; LRR; leucine-rich repeat; PFA; para-formaldehyde; PG; pollen grain; PT; pollen tube; PM; plasma membrane; RLK; rece

دانلود رایگان متن کامل مقاله ISI 13 صفحه سال انتشار : 2014 سفارش ترجمه

Hypoximimetic activity of N-acyl-dopamines. N-arachidonoyl-dopamine stabilizes HIF-1α protein through a SIAH2-dependent pathway

Keywords: هدایت سیگنال; AEA; N-arachidonoyl-ethanolamide; BNIP3; Bcl-2/E1B-nineteen kiloDalton interacting protein; CB1; cannabinoid receptor-1; EPO; erythropoietin; HBMECs; human brain microvascular endothelial cells; HUVECs; human umbilical vein endothelial cells; HIF; hypoxia

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

TGFβ and matrix-regulated epithelial to mesenchymal transition

Keywords: هدایت سیگنال; Epithelial-mesenchymal transition; Hyaluronan; Proteoglycan; Signal transduction; Transforming growth factor β; Tumor invasiveness;

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Type I interferons up-regulate the expression and signalling of p75 NTR/TrkA receptor complex in differentiated human SH-SY5Y neuroblastoma cells

Keywords: هدایت سیگنال; Type I interferons; Neurotrophins; p75NTR; TrkA; Signal transduction; Neuronal apoptosis; BDNF; brain-derived neurotrophic factor; CNS; central nervous system; DAPI; 4′,6-Diamidino-2phenylindole dihydrochloride; EAE; experimental allergic encephalomyeli

دانلود رایگان متن کامل مقاله ISI 14 صفحه سال انتشار : 2014 سفارش ترجمه

Protective effect of coconut water concentrate and its active component shikimic acid against hydroperoxide mediated oxidative stress through suppression of NF-κB and activation of Nrf2 pathway

Keywords: هدایت سیگنال; Coconut water concentrate; Shikimic acid; Ethnomedicine; Apoptosis; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Fibroblast growth factor (FGF) signaling in development and skeletal diseases

Keywords: هدایت سیگنال; Craniosynostosis; FGF signaling; Fibroblast growth factor; Fibroblast growth factor receptor; Genetics; Pathogenesis; Signal transduction; Skeletal development

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Proteomic identification of the molecular basis of mammalian CNS growth cones

Keywords: هدایت سیگنال; Axonal growth; Regeneration; Axon guidance; Cytoskeleton; Membrane trafficking; Signal transduction

دانلود رایگان متن کامل مقاله ISI 15 صفحه سال انتشار : 2014 سفارش ترجمه

Phosphoantigens and butyrophilin 3A1 induce similar intracellular activation signaling in human TCRVγ9+ γδ T lymphocytes

Keywords: هدایت سیگنال; BTN3A; butyrophilin 3A; BrHPP; bromohydrin pyrophosphate; mAb; monoclonal antibody; PAg; phosphoantigen; Activation; Cell barcoding; Gamma-delta; Phosphoflow cytometry; T lymphocytes; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 18 صفحه سال انتشار : 2014 سفارش ترجمه

PI3K Regulation of RAC1 Is Required for KRAS-Induced Pancreatic Tumorigenesis in Mice

Keywords: هدایت سیگنال; Pancreatic Cancer; Signal Transduction; Cytoskeleton; Oncogene; ADM; acinar-to-ductal metaplasia; DAPI; 4′,6-diamidino-2-phenylindole; EGFR; epidermal growth factor receptor; GAPDH; glyceraldehyde-3-phosphate dehydrogenase; GEF; guanine nucleotide excha

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Bone Morphogenetic Protein (BMP) signaling in development and human diseases

Keywords: هدایت سیگنال; BMP signaling; Development; Genetics; Mouse knockout; Pathogenesis; Signal transduction

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

Ribonucleoprotein HNRNPA2B1 Interacts With and Regulates Oncogenic KRAS in Pancreatic Ductal Adenocarcinoma Cells

Keywords: هدایت سیگنال; Signal Transduction; Carcinogenesis; Oncogene; Mouse Model; AKT; c-akt murine thymoma oncogene homolog 1; FCS; fetal calf serum; GFP; green fluorescent protein; GTP; guanosine triphosphate; HA; hemagglutinin; hnRNP; heterogeneous nuclear ribonucleoprotein

دانلود رایگان متن کامل مقاله ISI 19 صفحه سال انتشار : 2014 سفارش ترجمه

MAPK Signaling Is Required for Dedifferentiation of Acinar Cells and Development of Pancreatic Intraepithelial Neoplasia in Mice

Keywords: هدایت سیگنال; Pancreatic Cancer; Signal Transduction; Mouse Models; Acinar Differentiation; ADM; acinar-ductal metaplasia; ERK1/2; extracellular signal-regulated kinase1/2; iKras*; inducible-KrasG12D (p48Cre,TetO-KrasG12D,Rosa26rtTa-IRES-EGFP); KC; p48Cre,LSL-KrasG12D;

دانلود رایگان متن کامل مقاله ISI 20 صفحه سال انتشار : 2014 سفارش ترجمه

Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis via Activation of Rho and ROCK

Keywords: هدایت سیگنال; Colon Cancer; Signal Transduction; Transcription; Tumor Progression; BMP; bone morphogenetic protein; BMPR; bone morphogenetic protein receptor; CRC; colorectal cancer; EMT; epithelial-mesenchymal transition; GSK; glycogen synthase kinase; mRNA; messeng

دانلود رایگان متن کامل مقاله ISI 26 صفحه سال انتشار : 2014 سفارش ترجمه

An enhanced LSPR fiber-optic nanoprobe for ultrasensitive detection of protein biomarkers

Keywords: هدایت سیگنال; Fiber optics; Protein biomarker biosensors; Nanofabrication; Au nanodisk array; Localized surface plasmon resonance; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2014 سفارش ترجمه

Cyclophilin Inhibitors Reduce Phosphorylation of RNA-Dependent Protein Kinase to Restore Expression of IFN-Stimulated Genes in HCV-Infected Cells

Keywords: هدایت سیگنال; Signal Transduction; Cyclosporin; Innate Immunity; Replication; CsA; cyclosporin A; CyP; cyclophilin; HCV; hepatitis C virus; IFN; interferon; IL; interleukin; ISG; IFN-stimulated gene; mRNA; messenger RNA; PKR; double-strand RNA-dependent protein kinase;

دانلود رایگان متن کامل مقاله ISI 33 صفحه سال انتشار : 2014 سفارش ترجمه

The Bile Acid Receptor TGR5 Activates the TRPA1 Channel to Induce Itch in Mice

Keywords: هدایت سیگنال; Liver; Mouse Model; Itching; Signal Transduction; AITC; allyl isothiocyanate; BA; bile acid; DiI; dioctadecyl-3,3,3′,3′-tetramethylindocarbocyanine perchlorate; DCA; deoxycholic acid; DRG; dorsal root ganglia; GPCR; G-protein-coupled receptor; GRP;

دانلود رایگان متن کامل مقاله ISI 35 صفحه سال انتشار : 2014 سفارش ترجمه

ITF2 Prevents Activation of the β-Catenin-TCF4 Complex in Colon Cancer Cells and Levels Decrease With Tumor Progression

Keywords: هدایت سیگنال; Tumor Suppressor; Wnt Signaling; Signal Transduction; Mouse Model; APC; adenomatous polyposis coli; AR; armadillo repeat domain; bHLH; basic helix loop helix; CRC; colorectal cancer; CSC; cancer stem cells; DCC; deleted in colon cancer; GSEA; gene set enr

دانلود رایگان متن کامل مقاله ISI 48 صفحه سال انتشار : 2014 سفارش ترجمه

Down-regulation of MicroRNA-494 via Loss of SMAD4 Increases FOXM1 and β-Catenin Signaling in Pancreatic Ductal Adenocarcinoma Cells

Keywords: هدایت سیگنال; Pancreatic Cancer; Gene Regulation; Signal Transduction; Tumor Progression; FOXM1; Forkhead box M1; LMD; laser-assisted microdissection; miRNA; microRNA; mRNA; messenger RNA; PanIN; pancreatic intraepithelial neoplasia; PCR; polymerase chain reaction; PDA

دانلود رایگان متن کامل مقاله ISI 64 صفحه سال انتشار : 2014 سفارش ترجمه

Genetic insights into the in vivo functions of prostaglandin signaling

Keywords: هدایت سیگنال; Prostaglandins; Signal transduction; Cancer; Reproduction; Development;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

Induction of methionine sulfoxide reductase activity by pergolide, pergolide sulfoxide, and S-adenosyl-methionine in neuronal cells

Keywords: هدایت سیگنال; SAM; S-adenosyl-methionine; Msr; methionine sulfoxide reductase; MetO; methionine sulfoxide; Pergolide; S-adenosyl methionine; Oxidative stress; Post-translational modification; Signal transduction; Antioxidants;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

A repressor protein, Mnt, is a novel negative regulator of vascular smooth muscle cell hypertrophy by angiotensin II and neointimal hyperplasia by arterial injury

Keywords: هدایت سیگنال; Transcriptional repressor; Angioplasty; Gene therapy; Restenosis; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 4 صفحه سال انتشار : 2013 سفارش ترجمه

The NF-κB signalling pathway in osteoarthritis

Keywords: هدایت سیگنال; NF-κB; Osteoarthritis; Signal transduction; Chondrocytes; Cartilage destruction;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Real-time monitoring of intracellular signal transduction in PC12 cells by two-dimensional surface plasmon resonance imager

Keywords: هدایت سیگنال; 2D-SPR imaging; PC12 cell; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 5 صفحه سال انتشار : 2013 سفارش ترجمه

Structural insights into the activation of MST3 by MO25

Keywords: هدایت سیگنال; LB; Luria-Bertani; MST; mammalian sterile 20 (Ste20)-like kinase; MO25; mouse protein-25; PEI; polyethyleneimine; STRAD; STE20-related adapter protein; YSK1; yeast SPS/STE20-related kinase-1; Protein kinase; LKB1; Signal transduction; Protein structur

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه

The effect of CD137-CD137 ligand interaction on phospholipase C signaling pathway in human endothelial cells

Keywords: هدایت سیگنال; CD137; CD137 ligand; Phospholipase C; Endothelial; Cells; Signal transduction;

دانلود رایگان متن کامل مقاله ISI 6 صفحه سال انتشار : 2013 سفارش ترجمه