Differential expression of PKC isoforms in developing zebrafish
Keywords: پروتئین کیناز سی; Zebrafish; Protein kinase C; Development; Rohon-Beard; Mauthner cell
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Prostanoids in nociception and pain
Keywords: پروتئین کیناز سی; CFA; complete Freund's adjuvant; COX; cyclooxygenase (EC 1.14.99.1); CSF; cerebrospinal fluid; DRG; dorsal root ganglion; GlyRα3; glycine receptor α3 subunit; GST; glutathione S transferases; LPS; lipopolysaccharide; mPGES; microsomal prostaglandin E sy
Involvement of Gq/11 in both integrin signal-dependent and -independent pathways regulating endothelin-induced neural progenitor proliferation
Keywords: پروتئین کیناز سی; Neural progenitor cells; Endothelin; G proteins; Proliferation; Protein kinase C; Extracellular matrix; Paxillin;
Upregulation of Glucose-6-Phosphate Dehydrogenase and NAD(P)H Oxidase Activity Increases Oxidative Stress in Failing Human Heart
Keywords: پروتئین کیناز سی; Human heart; NAD(P)H oxidase; glucose-6-phosphate dehydrogenase; protein kinase C; Src kinase; free radicals
Huperzine A regulates amyloid precursor protein processing via protein kinase C and mitogen-activated protein kinase pathways in neuroblastoma SK-N-SH cells over-expressing wild type human amyloid precursor protein 695
Keywords: پروتئین کیناز سی; huperzine A; amyloid precursor protein; Aβ; protein kinase C; mitogen-activated protein kinase; muscarinic acetylcholine receptorAβ, amyloid-β peptide; AChE, acetylcholinesterase; AD, Alzheimer’s disease; ADAM, a disintegrin and metalloprotease; APP, amyl
Functional changes in the vanilloid receptor subtype 1 channel during and after acute desensitization
Keywords: پروتئین کیناز سی; capsaicin; vanilloid receptor; TRP channels; structure-function relationship; desensitization; CaMKII; Ca2+/calmodulin-dependent kinase II; GFP; green fluorescent protein; HEK; human embryonic kidney; I-V; current-voltage; PIP2; phosphatidylinositol 4
Protein kinase Cε mediates salutary effects on electrical coupling induced by ischemic preconditioning
Keywords: پروتئین کیناز سی; Connexin 43; Coupling; Gap junctions; Preconditioning; Protein kinase C
Phosphorylation of Ser166 in RGS5 by protein kinase C causes loss of RGS function
Keywords: پروتئین کیناز سی; G proteins; RGS5; Phosphorylation; Protein kinase C; GTPase-activating proteins
Ursodeoxycholic Acid Stimulates Cholangiocyte Fluid Secretion in Mice via CFTR-Dependent ATP Secretion
Keywords: پروتئین کیناز سی; CA; cholic acid; CFTR; cystic fibrosis transmembrane conductance regulator; EGF; epidermal growth factor; IBDU; isolated bile duct unit; KRB; NaHCO3/CO2-buffered Ringer; MEQ; 6-methoxy-N-ethylquinolinium chloride; P2Y; purinergic receptor 2Y; PKC; protein
TPA-induced multinucleation of a mesenchymal stem cell-like clone is mediated primarily by karyokinesis without cytokinesis, although cell–cell fusion also occurs
Keywords: پروتئین کیناز سی; Plasmodium; Syncytium; Mesenchymal stem cell; Cell–cell fusion; Phorbol ester; TPA; Multinucleation; Protein kinase C; Cytokinesis; Nuclear division
Phosphoinositide-dependent pathways in mouse sperm are regulated by egg ZP3 and drive the acrosome reaction
Keywords: پروتئین کیناز سی; PI3 kinase, 1-phosphatidylinositol-3-kinase; PI(3,4,5)P3, phosphatidylinositol(3,4,5)-triphosphate; ZPse, zona pellucida soluble extractFertilization; Acrosome reaction; Sperm; Akt; Protein kinase C; Phosphatidylinositol; Phosphatidylinositol 3-kinase; Ph
Nonreceptor Tyrosine Kinases in Prostate
Keywords: پروتئین کیناز سی; Nonreceptor tyrosine kinase; prostate cancer; Src; FAK; ETK; Abl; v-Abl Abelson murine leukemia viral oncogene homolog; At; androgenindependent; Aid; v-akt murine thymoma viral oncogene homolog 1; AR; androgen receptor; ARG; Abelson-related gene; Bcr; bre
Fas ligand-induced apoptosis is regulated by nitric oxide through the inhibition of fas receptor clustering and the nitrosylation of protein kinase Cε
Keywords: پروتئین کیناز سی; Nitrosylation; Apoptosis; Receptor clustering; Protein kinase C; Trophoblast;
Lysophosphatidylcholine produced by the phospholipase A2 isolated from Lachesis muta snake venom modulates natural killer activity as a protein kinase C effector
Keywords: پروتئین کیناز سی; Lysophosphatidylcholine; Phospholipase A2; Lachesis muta; Snake venom; Lymphocytes; Protein kinase C
Hemispheric differences in protein kinase C βII levels in the rat amygdala: Baseline asymmetry and lateralized changes associated with cue and context in a classical fear conditioning paradigm
Keywords: پروتئین کیناز سی; laterality; amygdala; protein kinase C; behavior; limbic system; asymmetryBLA, basal nucleus of the amygdala; CS, conditioned stimulus; EDTA, ethylenediaminetetraacetic acid; EGTA, ethylene glycol tetraacetic acid; LA, lateral nucleus of the amygdala; PKC
Evidence for a columnar organization of cones, Müller cells, and neurons in the retina of a cichlid fish
Keywords: پروتئین کیناز سی; mosaic; cone photoreceptor; bipolar cell; radial glia; Astatotilapia burtoni; GCL; ganglion cell layer; GS; glutamine synthetase; INL; inner nuclear layer; IPL; inner plexiform layer; OPL; outer plexiform layer; PKC; protein kinase C;
Initial three-dimensional reconstructions of protein kinase C δ from two-dimensional crystals on lipid monolayers
Keywords: پروتئین کیناز سی; PKC; protein kinase C; RD; regulatory domain; 3D; three-dimensional; 2D; two-dimensional; NMR; nuclear magnetic resonance; DOPC; dioleoylphosphatidylcholine; DOPS; dioleoylphosphatidylserine; DO; diolein; DAG; diacylglycerol; FRC; Fourier ring correlation
Sevoflurane immediate preconditioning alters hypoxic membrane potential changes in rat hippocampal slices and improves recovery of CA1 pyramidal cells after hypoxia and global cerebral ischemia
Keywords: پروتئین کیناز سی; preconditioning; sevoflurane; volatile anesthetics; ischemia; hypoxia; hippocampus; aCSF; artificial cerebrospinal fluid; CA1; cornus ammonis 1; PKC; protein kinase C; PKM; protein kinase M;
A role for diacylglycerol in annexin A7-mediated fusion of lung lamellar bodies
Keywords: پروتئین کیناز سی; DAG; diacylglycerol; DPE; dansyl phosphatidylethanolamine; F345; fluorescence at 345Â nm; PC; phosphatidylcholine; PE; phosphatidylethanolamine; PIP2; phosphatidylinositol-4,5-bisphosphate; PI; phosphatidylinositol; PS; phosphatidylserine; PKC; protein ki
Modulation of succinate transport in Hep G2 cell line by PKC
Keywords: پروتئین کیناز سی; Succinate; Citrate; Hep G2; Dicarboxylate; Protein kinase C; Protein kinase A
Mechanical stress-initiated signal transduction in vascular smooth muscle cells in vitro and in vivo
Keywords: پروتئین کیناز سی; AgIIR; angiotensin II receptor; cAMP; cyclic adenosine monophosphate; EC; endothelial cells; eNOS; endothelial nitric oxide synthase; ERK; extracellular signal-regulated kinase; GPCR; G protein-coupled receptor; IGFR; insulin-like growth factor receptor;
Amitriptyline preserves morphine’s antinociceptive effect by regulating the glutamate transporter GLAST and GLT-1 trafficking and excitatory amino acids concentration in morphine-tolerant rats
Keywords: پروتئین کیناز سی; Amitriptyline; Glutamate transporter; Trafficking; Protein kinase A; Protein kinase C; Morphine tolerance
Activation of GABA receptors attenuates neuronal apoptosis through inhibiting the tyrosine phosphorylation of NR2A by Src after cerebral ischemia and reperfusion
Keywords: پروتئین کیناز سی; cerebral ischemia; GABA receptor; NMDA receptor; muscimol; baclofen; Src; CAMK II; CaM-dependent protein kinase II; DAPI; 4â²,6-diamidino-2-phenylindole dihydrochloride; DMSO; dimethyl sulfoxide; EBSS; Earl's balanced salt solution; h-DMEM; high-glucos
Noradrenergic modulation of the hyperpolarization-activated cation current (Ih) in dopamine neurons of the ventral tegmental area
Keywords: پروتئین کیناز سی; VTA; Ih; norepinephrine; dopamine receptors; adrenergic receptors; ACSF; artificial cerebrospinal fluid; ANOVA; analysis of variance; DA; dopamine; DRG; dorsal root ganglion; EGTA; HTCaS, high-threshold calcium spike; MNTB; medial nucleus of the trapezoid
Activation of presynaptic kainate receptors suppresses GABAergic synaptic transmission in the rat globus pallidus
Keywords: پروتئین کیناز سی; IPSC; patch-clamp; striatum; PKC; paired-pulse facilitation; ACSF; artificial cerebrospinal fluid; ATPA; (RS)-2-amino-3-(3-hydroxy-5-tert-butylisoxazol-4-yl)propanoic acid; CNQX; 6-cynao-7-nitroquinoxaline-2,3-dione; CPPG; (RS)-α-cyclopropyl-4-phosphonop
Convergence of multiple signaling pathways is required to coordinately up-regulate mtDNA and mitochondrial biogenesis during T cell activation
Keywords: پروتئین کیناز سی; Mitochondria; mtDNA; Biogenesis; Protein kinase C; Calcium; Signaling; AMP-activated protein kinase; mTOR; Rapamycin; Ionomycin; Membrane potential; Oxidative phosphorylation; T cell; Cytokine; T cell receptor
Putative role of heparan sulfate proteoglycan expression and shedding on the proliferation and survival of cells after photodynamic therapy
Keywords: پروتئین کیناز سی; PDT; photodynamic therapy; PS; photosensitizer; ROS; reactive oxygen species; ECM; extracellular matrix; GAG; glycosaminoglycans; PG; proteoglycan; HS; heparan sulfate; DS; dermatan sulfate; CS; chondroitin sulfate; EC; endothelial cell; EJ-ras-EC; endoth
Inverse agonist-induced signaling and down-regulation of the platelet-activating factor receptor
Keywords: پروتئین کیناز سی; Platelet-activating factor; Inverse agonist; Protein kinase C; G-protein-coupled receptor; GPCR trafficking;
Ethanol induces apoptosis in hepatocytes by a pathway involving novel protein kinase C isoforms
Keywords: پروتئین کیناز سی; ALD; alcoholic liver disease; PKC; protein kinase C; MAPK; mitogen-activated protein kinase; ERK1/2; extracellular signaling-regulated kinase type 1 and type 2; JNK1/2; c-Jun N-terminal kinase type 1 and type 2; NF-κB; nuclear factor kappa B; AP-1; activ
Lung Cancer Chemoprevention : ACCP Evidence-Based Clinical Practice Guidelines (2nd Edition)
Keywords: پروتئین کیناز سی; acetyl salicylic acid; apoptosis; biomarkers; chemoprevention; cyclooxygenase-2 inhibitors; lung cancer; proliferation; protein kinase C; selenium; signal transduction pathways; tyrosine kinase inhibitors; vitamin A; vitamin EADT, anethole dithiolethione;
Mechanism of attenuation of angiotensin-II-induced protein degradation by insulin-like growth factor-I (IGF-I)
Keywords: پروتئین کیناز سی; Angiotensin II; Protein degradation, insulin-like growth factor-I; Protein kinase C; Protein kinase R; NF-κB
Iron dysregulation in Alzheimer's disease: Multimodal brain permeable iron chelating drugs, possessing neuroprotective-neurorescue and amyloid precursor protein-processing regulatory activities as therapeutic agents
Keywords: پروتئین کیناز سی; AD; Alzheimer's disease; ALS; amyotrophic lateral sclerosis; APP; amyloid precursor protein; BDNF; brain-derived neurotrophic factor; Aβ; beta-amyloid peptide; β-CTF; beta-C-terminal fragment; EGCG; epigallocatechin gallate; DFO; desferrioxamine; ERK1/2
Protein kinase C dependent inhibition of the heteromeric Kir4.1–Kir5.1 channel
Keywords: پروتئین کیناز سی; Kir4.1–Kir5.1; Protein kinase C; Phosphorylation; Endocytosis
Cardioprotective mechanisms of PKC isozyme-selective activators and inhibitors in the treatment of ischemia-reperfusion injury
Keywords: پروتئین کیناز سی; Ischemia; Reperfusion injury; Preconditioning; Peptide modulators; Protein kinase C
Diacylglycerol kinases: Why so many of them?
Keywords: پروتئین کیناز سی; Diacylglycerol kinase; Phosphatidic acid; Isozyme; Protein kinase C; Signal transduction; C1 domain;
The role of volume-sensitive ion transport systems in regulation of epithelial transport
Keywords: پروتئین کیناز سی; NKCC; Na+, K+, 2Clâ; RVI; volume regulatory increase; EATC; Ehrlich ascites tumour cells; SK; K channels having small conductance; IK; intermediate conductance; BK; large conductance; 2P-4TM; four transmembrane-spanning segments; TASK-2; acid sensitive
Cerebellar cortical-layer-specific control of neuronal migration by pituitary adenylate cyclase-activating polypeptide
Keywords: پروتئین کیناز سی; cerebellar development; granule cell; neuronal cell migration; cAMP; rate of cell movement; desensitization; E; embryonic day; EGL; external granular layer; Erk; extracellular signal-regulated; GalR1; galanin receptor 1; GRK; G-protein-coupled receptor ki
Brain regions and genes affecting postural control
Keywords: پروتئین کیناز سی; P; postnatal; PKC; protein kinase C; MPTP; methyl-phenyl-tetrahydroyridine; 6-OHDA; 6-hydroxydopamine; CO; cytochrome oxidase; EMG; electromyographic; Cerebellum; Basal ganglia; Motor coordination; Motor cortex; Gene knockout;
Ca++ influx is essential for the hypotensive response to arginine vasopressin-induced neuron activation of the area postrema in the rat
Keywords: پروتئین کیناز سی; Arginine vasopressin; Hypotension; V1A receptor; Phospholipase C; Protein kinase C; Ca++ channel; Rat
Apoptosis and the cardiac action of insulin-like growth factor I
Keywords: پروتئین کیناز سی; Insulin-like growth factor; Apoptosis; Myocardium; Ischaemia; Reperfusion injury; Signaling; ARC; apoptotic repressor with CARD; ATP; adenosine triphosphate; bFGF; basic fibroblast growth factor (also known as FGF2); BAK; Bcl-2 antagonist/killer protein;
Effect of 8-bromo-cAMP on the tetrodotoxin-resistant sodium (Nav 1.8) current in small-diameter nodose ganglion neurons
Keywords: پروتئین کیناز سی; Nodose ganglion; 8-Bromo-cyclic AMP; Tetrodotoxin-resistant sodium current; Protein kinase A; Protein kinase C; Internal application
N-Methyl-d-aspartate (NMDA) receptor function and excitotoxicity in Huntington's disease
Keywords: پروتئین کیناز سی; 3-NP; 3-nitropropionic acid; ADP; adenosine 5â²-diphosphate; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid; AMPAR; AMPA receptor; AP-2; adaptor protein-2; ATP; adenosine 5â²-triphosphate; cAMP; cyclic adenosine 5â²-monophosphate; CNS; ce
(±)3,4-Methylenedioxyamphetamine elicits action potential bursts in a central snail neuron
Keywords: پروتئین کیناز سی; 3,4-Methylenedioxyamphetamine; Neuron; Snail; Action potential bursts; Protein kinase C; Ionic currents;
The role of mitochondria in protection of the heart by preconditioning
Keywords: پروتئین کیناز سی; 5HD; 5-hydroxydecanoate; AMPK; AMP activated protein kinase; ANT; Adenine nucleotide translocase; APD; Action potential duration; BCDH; branched chain 2-oxoacid dehydrogenase; CrK; creatine kinase; CsA; cyclosporin A; CyP; cyclophilin; Cx43; connexin43; G
l-DOPA treatment of parkinsonian rats changes the expression of Src, Lyn and PKC kinases
Keywords: پروتئین کیناز سی; Dopamine; Glutamate; 6-Hydroxydopamine; Protein kinase C; Lyn and Src kinases
High glucose exacerbates neutrophil adhesion to human retinal endothelial cells
Keywords: پروتئین کیناز سی; diabetic retinopathy; leukocyte; protein kinase C; intercellular adhesion molecule-1; vascular inflammation
A novel approach to model neuronal signal transduction using stochastic differential equations
Keywords: پروتئین کیناز سی; Stochastic differential equation; Itô form; Euler–Maruyama method; Protein kinase C; Signal transduction
The C-terminal tail of protein kinase D2 and protein kinase D3 regulates their intracellular distribution
Keywords: پروتئین کیناز سی; Protein kinase D; Protein kinase D2; Protein kinase D3; Intracellular distribution; Imaging; G protein-coupled receptor; Green fluorescent protein; Protein kinase C
Glycated albumin (Amadori product) induces activation of MAP kinases in monocyte-like MonoMac 6 cells
Keywords: پروتئین کیناز سی; AGEs; advanced glycation end products; AP-1; activator protein-1; ERK; extracellular signal-regulated kinase; GA; glycated albumin; IL-1β; interleukin 1β; MAPK; mitogen-activated protein kinases; NA; native, nonglycated albumin; NF-κB; nuclear factor-Î
Inhibition and down-regulation of gene transcription and guanylyl cyclase activity of NPRA by angiotensin II involving protein kinase C
Keywords: پروتئین کیناز سی; Natriuretic peptide receptor; Npr1 promoter; Gene transcription; Protein kinase C; Mesangial cells