Protein kinase C and the regulation of the actin cytoskeleton
Keywords: پروتئین کیناز سی; Protein kinase C; Actin; Integrins; Cell movement; Neurite; Stress fibers
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Partial replacement of cardiac troponin I with a non-phosphorylatable mutant at serines 43/45 attenuates the contractile dysfunction associated with PKCε phosphorylation
Keywords: پروتئین کیناز سی; Sarcomeric proteins; Heart failure; Protein kinase C; Troponin I
Role of nitric oxide/cyclic GMP and cyclic AMP in β3 adrenoceptor-chronotropic response
Keywords: پروتئین کیناز سی; Heart contractility; β3 Adrenoceptor; Nitric oxide; Nitric oxide synthase; Phospholipase C; Protein kinase C; Phosphoinositides hydrolysis
Protein kinase C α trigger Ras and Raf-independent MEK/ERK activation for TPA-induced growth inhibition of human hepatoma cell HepG2
Keywords: پروتئین کیناز سی; 12-O-Tetradecanoylphorbol-13-acetate; Protein kinase C; ERK; MEK; HepG2
Structure prerequisite for antioxidant activity of silybin in different biochemical systems in vitro
Keywords: پروتئین کیناز سی; Silybin; Oxidative stress; Antioxidants; Protein kinase C; Xanthine oxidase; Low density lipoproteinPKC, protein kinase C; NADPH, nicotinamide adenine dinucleotide phosphate; PMA, phorbol myristate acetate; LDL, low density lipoprotein; Ca, calcium; PS, p
Upstream signaling of protein kinase C-ε in xenon-induced pharmacological preconditioning: Implication of mitochondrial adenosine triphosphate dependent potassium channels and phosphatidylinositol-dependent kinase-1
Keywords: پروتئین کیناز سی; Anaesthetic preconditioning; Xenon; Cardiac preconditioning; Mitochondrial adenosine triphosphate dependent potassium channel; Protein kinase C; 3′Phosphatidylinositol-dependent kinase-1
Involvement of protein kinase C in 5-HT-evoked thermal hyperalgesia and spinal fos protein expression in the rat
Keywords: پروتئین کیناز سی; 5-HT; 5-hydroxytryptamine; 8-OH-DPAT; (±)-8-hydroxy-2-(di-n-propylamino)tetralin; α-m-5-HT; α-methylserotonin; c-fos-LI; c-Fos-like immunoreactivity; DMSO; dimethylsulphoxide; i.pl.; intraplantar or intraplantarly; PBS; phosphate-buffered saline; PKC;
Modulation of Na, K-ATPase activity by prostaglandin E1 and [d-Ala2,N-Me-Phe4,Gly5-ol]-enkephalin
Keywords: پروتئین کیناز سی; Calcium; DAMGO; PGE1; Protein kinase A; Protein kinase C; Sodium pump; SH-SY5Y
Effects of PKC412, Nilotinib, and Imatinib Against GIST-Associated PDGFRA Mutants With Differential Imatinib Sensitivity
Keywords: پروتئین کیناز سی; Bcr-Abl; breakpoint cluster region-Abelson; GIST; gastrointestinal stromal tumor; PDGFR; platelet-derived growth factor receptor; PDGFRA; platelet-derived growth factor receptor α; PKC; protein kinase C;
Angiotensin II promotes the proliferation of activated pancreatic stellate cells by Smad7 induction through a protein kinase C pathway
Keywords: پروتئین کیناز سی; Angiotensin II; Pancreatic stellate cell; Proliferation; Smad; TGF-β; Protein kinase C; NF-κB
Phosphorylation at the hydrophobic site of protein kinase C Apl II is increased during intermediate term facilitation
Keywords: پروتئین کیناز سی; Aplysia; learning and memory; phosphoinositide dependent kinase I; persistent protein kinase; rapamycin; autophosphorylation; PDBu; phorbol dibutyrate; PDK-1; phosphoinositide-dependent kinase I; PI-3 kinase; phosphoinositide-3 kinase; PKC; protein kinase
Evidence that protease-activated receptor-2 mediates trypsin-induced reversal of stellation in cultured rat astrocytes
Keywords: پروتئین کیناز سی; Trypsin; Protease-activated receptor-2; Reversal of stellation; Rat primary astrocyte cultures; Ca2+; Protein kinase C
Regulatory properties and cellular redistribution of zinc during macrophage differentiation of human leukemia cells
Keywords: پروتئین کیناز سی; Biometals; Differentiation; Myeloid; Protein kinase C; Zinc
Tocopherol-mediated modulation of age-related changes in microglial cells: Turnover of extracellular oxidized protein material
Keywords: پروتئین کیناز سی; AGE; advanced glycation end products; BSA; bovine serum albumin; DMEM; Dulbecco's modified Eagle's medium; IFN; interferon; IL; interleukin; DMSO; dimethyl sulfoxide; HBSS; Hank's balanced salt solution; MBP; myelin basic protein; PKC; protein kinase C; P
Differential effects of PCBs on the induction of apoptosis machinery and PKCα translocation in rat renal tubular cell cultures
Keywords: پروتئین کیناز سی; Protein kinase C; PKCα; Polychlorinated biphenyls; PCB congeners; Renal cell cultures; Caspases; Bcl-2;
Piceatannol upregulates endothelial heme oxygenase-1 expression via novel protein kinase C and tyrosine kinase pathways
Keywords: پروتئین کیناز سی; Endothelial cells; Heme oxygenase-1; Piceatannol; Protein kinase C
Phospholipase D from photoreceptor rod outer segments is a downstream effector of RhoA: Evidence of a light-dependent mechanism
Keywords: پروتئین کیناز سی; retina; rod outer segments; phospholipase D; RhoA; phosphatidic acid; protein kinase A; protein kinase C
Substance P induces expression of the corticotropin-releasing factor receptor 1 by activation of the neurokinin-1 receptor
Keywords: پروتئین کیناز سی; CRF1 receptor; corticotropin-releasing factor receptor; MAPK; mitogen-activated protein kinase; NK; neurokinin; NK-1-R; neurokinin-1 receptor; PKC; protein kinase C; SP; substance P; Affective disorder; Depression; HPA axis; Somatostatin receptor type 4;
Sustained activation of Src-family tyrosine kinases by ischemia: A potential mechanism mediating extracellular signal-regulated kinase cascades in hippocampal dentate gyrus
Keywords: پروتئین کیناز سی; cerebral ischemia; ERKs; Raf-1; Ras; RKIP; Src family tyrosine kinases; ERK; extracellular signal-regulated kinase; IP; immunoprecipitation; locostatin; (4S)-3-[(E)-but-2-enoyl]-4-benzyl-2-oxazolidinone; NMDAR; NMDA receptor; p-ERK; phosphorylated extrace
Facilitatory effect of aspirin on glutamate release from rat hippocampal nerve terminals: Involvement of protein kinase C pathway
Keywords: پروتئین کیناز سی; Aspirin; Ca2+ influx; Protein kinase C; Glutamate exocytosis; Hippocampal synaptosomes
Cytotoxic mechanisms of Zn2+ and Cd2+ involve Na+/H+ exchanger (NHE) activation by ROS
Keywords: پروتئین کیناز سی; Na+/H+ exchanger; ROS; Protein kinase C; Adrenergic receptors; PPAR-γ agonists; Oxidants
Nuclear protein kinase C
Keywords: پروتئین کیناز سی; Nucleus; Protein kinase C; Signal transduction; Phosphorylation; Gene expression; Lipid second messengers
Mechanism of induction of muscle protein degradation by angiotensin II
Keywords: پروتئین کیناز سی; Angiotensin I/II; Protein degradation; Protein kinase C; NF-κB
2-Benzyl and 2-phenyl-3-hydroxypropyl pivalates as protein kinase C ligands
Keywords: پروتئین کیناز سی; Protein kinase C; Diacylglycerol; Phorbol ester
Protein kinase C (PKC) family in cancer progression
Keywords: پروتئین کیناز سی; Cancer; Protein kinase C; Carcinogenesis
A novel method for detecting neutralizing antibodies against therapeutic proteins by measuring gene expression
Keywords: پروتئین کیناز سی; BL; blocker; CE; capture extender; EPO; erythropoietin; LE; label extender; GM-CSF; granulocyte-macrophage colony-stimulating factor; MAPK; MAP kinase; PI3-K; phosphatidylinositol 3-kinase; PKA; protein kinase A; PKC; protein kinase C; r; recombinant; S
Protein kinase C attenuates β-adrenergic receptor-mediated lipolysis, probably through inhibition of the β1-adrenergic receptor system
Keywords: پروتئین کیناز سی; Adipocyte; Lipolysis; Protein kinase C; β-Adrenergic receptor; Phorbol 12-myristate 13-acetate
Essential role of the LIM domain in the formation of the PKCɛ–ENH–N-type Ca2+ channel complex
Keywords: پروتئین کیناز سی; Voltage-gated calcium channels; Modulation; Protein kinase C; Enigma homolog; Calcium; Signal transduction; Synaptic transmission
Calcitriol modulation of cardiac contractile performance via protein kinase C
Keywords: پروتئین کیناز سی; Vitamin D; Calcitriol; Cardiac myocyte; Contractile function; Protein kinase C
Role of protein kinase C δ in curcumin-induced antioxidant response element-mediated gene expression in human monocytes
Keywords: پروتئین کیناز سی; Monocyte; Antioxidant response element; Heme oxygenase-1; Glutamyl cysteine ligase; Curcumin; Protein kinase C; Nrf2
Stretch-induced triphosphorylation of myosin light chain and myogenic tone in canine basilar artery
Keywords: پروتئین کیناز سی; Cerebral artery; Mechanical stretch; Myosin phosphorylation; Protein kinase C; Rho-kinase; Shortening velocity;
The Hepatitis C Envelope 2 Protein Inhibits LFA-1-Transduced Protein Kinase C Signaling for T-Lymphocyte Migration
Keywords: پروتئین کیناز سی; ICAM-1; intracellular adhesion molecule 1; LFA-1; leukocyte function-associated molecule-1; MIP; macrophage inflammatory protein; NK; natural killer; PBTL; peripheral blood T lymphocytes; PKC; protein kinase C; TCR; T-cell receptor;
SmPKC1, a new protein kinase C identified in the platyhelminth parasite Schistosoma mansoni
Keywords: پروتئین کیناز سی; Protein kinase C; Schistosoma mansoni; Parasite; Signal transduction; Gene
Signal transduction pathways triggered by selective formylpeptide analogues in human neutrophils
Keywords: پروتئین کیناز سی; Human neutrophil; Formylpeptide; Chemotaxis; Superoxide anion release; Protein kinase C; MAP kinase
Pharmacological evidence for activation of phospholipid and small GTP binding protein signalling cascades by Nod factors
Keywords: پروتئین کیناز سی; Actin; G-proteins; Phosphatidylinositol 3-kinase; Phospholipase C; Protein kinase C; Small GTPasesB & D solution, Broughton and Dilworth solution; DPA, 12-deoxyphorbol 13-acetate; Gαcommon, the common region of the Gα subunit; IP3, inositol trisphosphate;
Regulation of death and survival in astrocytes by ADP activating P2Y1 and P2Y12 receptors
Keywords: پروتئین کیناز سی; BrdUTP; 5-bromo-2â²-deoxyuridine 5â²-triphosphate; caspase-3; cytosolic aspartate-specific protease-3; DMEM; Dulbecco's modified Eagle's medium; Erk1/2; extracellular signal-regulated protein kinases 1 and 2; FACS; fluorescence-activated cell sorting; F
PKC-βII sensitizes cardiac myofilaments to Ca2+ by phosphorylating troponin I on threonine-144
Keywords: پروتئین کیناز سی; Phosphorylation; Protein kinase A; Protein kinase C; Myosin light chain kinase; Heart failure
Local anaesthetics inhibit signalling of human NMDA receptors recombinantly expressed in Xenopus laevis oocytes: role of protein kinase C
Keywords: پروتئین کیناز سی; anaesthetics; local; complications, hyperalgesia; oocytes; Xenopus laevis; protein kinase C; receptors, NMDA;
The tripeptide phenylalanine-(d) glutamate-(d) glycine modulates leukocyte infiltration and oxidative damage in rat injured spinal cord
Keywords: پروتئین کیناز سی; iNOS; gp91phox; lipid peroxidation; cell death; inflammation; free radical formation; ANOVA; analysis of variance; DCF; 2â²-7â²-dichlorofluorescein; DCFH-DA; 2â²,7â²-dichlorofluorescin-diacetate; fdG; phenylalanine-(d) aspartate-(d) glycine; feG; phen
From endothelium-derived hyperpolarizing factor (EDHF) to angiogenesis: Epoxyeicosatrienoic acids (EETs) and cell signaling
Keywords: پروتئین کیناز سی; Angiogenesis; Ca2+-dependent K+ channels; Cytochrome P450; Eicosanoids; Endothelium; Hyperpolarization; Membrane potential; Signal transduction; bFGF; basic fibroblast growth factor; BKCa channels; large conductance KCa+ channels; COX; cyclooxygenase; cyc
Stimulation of cyclic AMP formation and nerve electrical activity by octopamine in the terminal abdominal ganglion of the female gypsy moth Lymantria dispar
Keywords: پروتئین کیناز سی; CaM; calmodulin; FSK; forskolin; LSCM; laser scanning confocal microscopy; PKA; protein kinase A; PKC; protein kinase C; PMA; phorbol 12-myristate 13-acetate; PS; l-α-phosphatidyl-l-serine; TAG; terminal abdominal ganglion; TMR-DA; tetramethylrhodamine-c
ERK is an anti-inflammatory signal that suppresses expression of NF-κB-dependent inflammatory genes by inhibiting IKK activity in endothelial cells
Keywords: پروتئین کیناز سی; VEGF; vascular endothelial growth factor; HUVECs; human umbilical vein endothelial cells; bFGF; basic fibroblast growth factor; EGF; epidermal growth factor; TNF-α; tumor necrosis factor-α; IL-1β; interleukin-1β; KDR; Flk-1/kinase-insert domain contai
The very C-terminus of protein kinase CÉ is critical for the full catalytic competence but its hydrophobic motif is dispensable for the interaction with 3-phosphoinositide-dependent kinase-1
Keywords: پروتئین کیناز سی; aPKC; atypical PKC; cPKC; classic PKC; MD; molecular dynamics; nPKC; novel PKC; PAGE; polyacrylamide gel electrophoresis; PDK-1; 3-phosphoinositide-dependent kinase-1; PKA; cAMP-dependent protein kinase; PKB; protein kinase B; PKC; protein kinase C; RMSD;
Assembly of tight junction is regulated by the antagonism of conventional and novel protein kinase C isoforms
Keywords: پروتئین کیناز سی; Tight junctions; Occludin; Protein kinase C; Paracellular tightness
Tyrosine kinase modulation of protein kinase C activity regulates G protein-linked Ca2+ signaling in leukemic hematopoietic cells
Keywords: پروتئین کیناز سی; Tyrosine kinase; Protein kinase C; Store-operated calcium entry (SOCE); Leukemia cells; Bcr/Abl; G protein-coupled receptors
Norepinephrine-induced changes in gene expression of phospholipase C in cardiomyocytes
Keywords: پروتئین کیناز سی; Adult cardiomyocytes; α1-adrenoceptors; Phospholipase isozymes; Protein kinase C; Extracellular signal regulated kinase; Signal transduction; Cardiac gene expression
Regulation of human papillomavirus type 31 late promoter activation and genome amplification by protein kinase C
Keywords: پروتئین کیناز سی; Papillomavirus; Transcription; Replication; Cell signaling; Protein kinase C; Differentiation; Keratinocyte
PKCη is localized in the Golgi, ER and nuclear envelope and translocates to the nuclear envelope upon PMA activation and serum-starvation:
Keywords: پروتئین کیناز سی; Protein kinase C; PKCη; Nuclear envelope (NE); Pseudosubstrate (PS); Golgi localization; GFP-protein fusion; Phorbol esters; Serum-starvation;
Induction of protein degradation in skeletal muscle by a phorbol ester involves upregulation of the ubiquitin–proteasome proteolytic pathway
Keywords: پروتئین کیناز سی; Protein kinase C; Proteasome proteolysis; Nuclear factor-κB
Effects of the anti-neoplastic agent ET-18-OCH3 and some analogs on the biophysical properties of model membranes
Keywords: پروتئین کیناز سی; DEPE; 1,2-dieladoyl-sn-glycero-3-phosphoethanolamine; DMPC; 1,2-dimyristoyl-sn-glycero-3-phosphocholine; DSC; differential scanning calorimetry; EDTA; ethylenediaminetetraacetic acid; ET-16-OCH3-Ser; 1-O-hexadecyl-2-O-methyl-sn-glycero-3-phosphocholine; E