Keywords: پروتئین پریون; Multiple system atrophy; PRNP; Prion disease; Prion protein; Sporadic Creutzfeld-Jakob disease; α-synuclein; α-syn; confidence intervals; CI; cytoplasmic inclusions; GCIs; multiple system atrophy; MSA; sporadic Creutzfeld-Jakob disease; sCJD; odds ratio
مقالات ISI پروتئین پریون (ترجمه نشده)
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Keywords: پروتئین پریون; Prion protein; Anchorless; Truncation; Stop mutation; Amyloid;
Keywords: پروتئین پریون; Experimental autoimmune encephalomyelitis; Amyloid; Prion protein
Keywords: پروتئین پریون; PrP; prion protein; PrPc; normal cellular PrP; PrPres; protease-resistant abnormal PrP; JH-III; juvenile hormone III; FOH; farnesol; GGOH; geranylgeraniol; Isoprenoid; Prion; Juvenile hormone; Farnesol; Geranylgeraniol; Cholesterol; Prenylation; N2a cell;
Keywords: پروتئین پریون; DAPI; 4â²,6-diamidino-2-phenylindole; Iba-1; ionized calcium binding adaptor molecule-1; IL; interleukin; iNOS; inducible nitric oxide synthase; LPS; lipopolysaccharide; NF-κB; nuclear transcription factor kappa B; NO; nitric oxide; PrPC; prion protein;
Keywords: پروتئین پریون; prion protein; scrapie; sheep; transmissible spongiform encephalopathy
Truncated prion protein PrP226* - A structural view on its role in amyloid disease
Keywords: پروتئین پریون; Prion protein; Stop mutation; Truncation; NMR structure;
Research reportPrP-C1 fragment in cattle brains reveals features of the transmissible spongiform encephalopathy associated PrPsc
Keywords: پروتئین پریون; TSE; transmissible spongiform encephalopathy; BSE; bovine spongiform encephalopathy; PK; proteinase K; PrP; prion protein; PrPres; protease-resistant prion protein; PrPsc; disease-associated PrP; PrPc; normal cellular PrP; NaPTA; sodium phosphotungstic ac
Identification and Structural Characterization of the Precursor Conformation of the Prion Protein which Directly Initiates Misfolding and Oligomerization
Keywords: پروتئین پریون; PrP; prion protein; PrPC; cellular PrP; PrPSc; scrapie PrP; HDX; hydrogen-deuterium exchange; moPrP; mouse PrP; PUF; partially unfolded form; CTD; C-terminal domain; dm CTD; double mutant variant of the C-terminal domain; wt; wild-type; DLS; dynamic lig
Specific binding modes of Cu(I) and Ag(I) with neurotoxic domain of the human prion protein
Keywords: پروتئین پریون; Prion protein; Cu(I); Ag(I); Probe; Redox activity; His and Met residues; Amyloidogenic region
Roles of methionine oxidation in E200K prion protein misfolding: Implications for the mechanism of pathogenesis in E200K linked familial Creutzfeldt–Jakob disease
Keywords: پروتئین پریون; Prion protein; Methionine oxidation; Oxidative stress; Misfolding; E200K mutant; Familial Creutzfeldt–Jakob disease
Are prions transported by plasma exosomes?
Keywords: پروتئین پریون; Prion protein; Blood; Plasma; Extracellular vesicles; Prion infectivity;
Coomassie brilliant blue R-250 as a new surface-enhanced Raman scattering probe for prion protein through a dual-aptamer mechanism
Keywords: پروتئین پریون; Prion protein; Aptamer; Surface-enhanced Raman scattering; Ag@Si NPs; Protein labeling
Molecular-level insights of early-stage prion protein aggregation on mica and gold surface determined by AFM imaging and molecular simulation
Keywords: پروتئین پریون; Prion protein; Early-stage aggregation; Interfaces; Computational simulations; Atomic force microscopy
Prion protein-coated magnetic beads: Synthesis, characterization and development of a new ligands screening method
Keywords: پروتئین پریون; Prion protein; Ligand fishing; Magnetic beads; Anti-prion compounds; Quinacrine; Screening method
Research reportDeletion of the prion gene Prnp affects offensive aggression in mice
Keywords: پروتئین پریون; Prnp knockout mouse; Brain; Prion protein; Offensive aggression; Testosterone;
Identical Pathogenesis and Neuropathological Phenotype of Scrapie in Valine, Arginine, Glutamine/Valine, Arginine, Glutamine Sheep Infected Experimentally by the Oral and Conjunctival Routes
Keywords: پروتئین پریون; pathogenesis; prion protein; scrapie; sheep
Prion protein (PrPc) interacts with histone H3 confirmed by affinity chromatography
Keywords: پروتئین پریون; Prion protein; Histone H3; Interaction; Affinity chromatography
Silencing of PrPC (prion protein) expression does not affect Brucella melitensis infection in human derived microglia cells
Keywords: پروتئین پریون; Brucella; Inflammation; Antioxidant system; Microglia; Prion protein; siRNA
Distribution of Abnormal Prion Protein in a Sheep affected with L-type Bovine Spongiform Encephalopathy
Keywords: پروتئین پریون; atypical BSE; L-type BSE; prion protein; sheep
Metal-enhanced fluorescence of nano-core–shell structure used for sensitive detection of prion protein with a dual-aptamer strategy
Keywords: پروتئین پریون; Metal-enhanced fluorescence; Prion protein; Aptamer; Ag@Si nanoparticles
Insertion of beta-alanine in model peptides for copper binding to His96 and His111 of the human prion protein
Keywords: پروتئین پریون; Copper; Prion protein; β-Peptides; Chelate effect; Circular dichroism; Electron paramagnetic resonance
Specific metal ion binding sites in unstructured regions of proteins
Keywords: پروتئین پریون; α-synuclein; Cys-Cys binding sites; Cysteines; Histidines; Extra stability effects; Met containing regions; Metal ion binding; Polyhistidine sequences; Prion protein; Unstructured binding sites; ZIP and Znt transporters
Targeted mutation of the gene encoding prion protein in zebrafish reveals a conserved role in neuron excitability
Keywords: پروتئین پریون; NMDA receptor; Prion protein; Seizure susceptibility; Targeted mutagenesis
Depressive-like behaviour of mice lacking cellular prion protein
Keywords: پروتئین پریون; Prion protein; Depression; Knockout mice; Forced swimming test; Tail suspension test; Nmda receptor
Association of prion protein with cognitive functioning in humans
Keywords: پروتئین پریون; Prion protein; Epidemiological study; Homo sapiens; Cognition; Executive function
Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity
Keywords: پروتئین پریون; Resveratrol; Autophagy; Prion protein; Mitochondrial dysfunction
Increased Immunohistochemical Labelling for Prion Protein Occurs in Diverse Neurological Disorders of Sheep: Relevance for Normal Cellular PrP Function
Keywords: پروتئین پریون; prion disease; prion protein; scrapie; transmissible spongiform encephalopathy
Detergents modify proteinase K resistance of PrPSc in different transmissible spongiform encephalopathies (TSEs)
Keywords: پروتئین پریون; Prion protein; Scrapie; BSE; Chronic wasting disease; Proteinase resistance; Detergent
Squirrel Monkeys (Saimiri sciureus) Infected with the Agent of Bovine Spongiform Encephalopathy Develop Tau Pathology
Keywords: پروتئین پریون; bovine spongiform encephalopathy; prion protein; squirrel monkey; tau protein
Affinity of copper and zinc ions to proteins and peptides related to neurodegenerative conditions (Aβ, APP, α-synuclein, PrP)
Keywords: پروتئین پریون; Copper; Zinc; α-Synuclein; Amyloid β peptide; Prion protein; Amyloid precursor protein
The rich electrochemistry and redox reactions of the copper sites in the cellular prion protein
Keywords: پروتئین پریون; Prion protein; Copper binding; Electrochemistry; Redox reactions; Oxidative stress
Can Parkinson's disease pathology be propagated from one neuron to another?
Keywords: پروتئین پریون; AD; Alzheimer's disease; PD; Parkinson's disease; αsyn; α-synuclein; RBD; REM sleep behavior disorder; NAC; non-amyloid component; GWAS; genome wide association studies; TNTs; tunneling nanotubes; PrP; prion protein; Aβ; amyloid beta; MTBR; microtubule
Neurodegenerative diseases and exposure to the environmental metals Mn, Pb, and Hg
Keywords: پروتئین پریون; Metals; Mn; Pb; Hg; Exposure; Speciation; Neurodegenerative diseases; Prion protein; Amyloid beta, α-Synuclein
Serial diffusion-weighted MRI and SPECT findings in a Creutzfeldt–Jakob disease patient with V180I mutation
Keywords: پروتئین پریون; Creutzfeldt–Jakob disease; Magnetic resonance imaging; SPECT; Prion protein
Salt bridges in prion proteins are necessary for high-affinity binding to the monoclonal antibody T2
Keywords: پروتئین پریون; BSE; bovine spongiform encephalopathy; CD; circular dichroism; ka; association rate constant; kd; dissociation rate constant; KD; dissociation constant; PAGE; polyacrylamide gel electrophoresis; PrP; prion protein; PrPC; cellular prion protein; PrPSc; abn
Cellular prion protein localizes to the nucleus of endocrine and neuronal cells and interacts with structural chromatin components
Keywords: پروتئین پریون; Islets; β-cell; Prion protein; Nucleus; Histone H3; Lamin B1
A duplex approach for immunochemical staining and typing of proteins in Western blots
Keywords: پروتئین پریون; Immunoblot; Characterization; Duplex staining; Prion protein; Protein typing
Normal prion protein in Drosophila enhances the toxicity of pathogenic polyglutamine proteins and alters susceptibility to oxidative and autophagy signaling modulators
Keywords: پروتئین پریون; Prion protein; Drosophila; Polyglutamine; Oxidative stress; ER stress; Autophagy
Fate of prions in soil: Degradation of recombinant prion in aqueous extracts from soil and casts of two earthworm species
Keywords: پروتئین پریون; TSE; Prion protein; Degradation; Proteases; Earthworm; Bacteria; Fungi
Creutzfeldt - Jakob con debut oftalmológico: la variante Heidenhain
Keywords: پروتئین پریون; Enfermedad de Creutzfeldt-Jacob; Variante Heidenhain; Encefalopatía espongiforme; Proteína prionica; Pérdida de agudeza visual; Función visualCreutzfeldt-Jakob disease; Heidenhain variant; Spongiform encephalopathy; Prion protein; Visual acuity loss; Visu
Sensitive detection of scrapie prion protein in soil
Keywords: پروتئین پریون; GLS, Gray Lowland soils; LHA, Low-humic AndosolsScrapie; Chandler strain; Prion protein; Protein misfolding cyclic amplification; Soil
Ionic control of the metastable inner leaflet of the plasma membrane: Fusions natural and artefactual
Keywords: پروتئین پریون; Ca2+; Detergent-resistant membrane; Phosphatidylethanolamine; Phosphatidylserine; Prion protein; Thy-1
Automated decontamination of surface-adherent prions
Keywords: پروتئین پریون; Creuzfeldt–Jakob disease; Decontamination; Prion protein; Transmissible spongiform encephalopathies
Amino acid conditions near the GPI anchor attachment site of prion protein for the conversion and the GPI anchoring
Keywords: پروتئین پریون; Prion protein; Mutation; Glycosylphosphatidylinositol anchor; Conversion; ω Site
Microdeletions within the hydrophobic core region of cellular prion protein alter its topology and metabolism
Keywords: پروتئین پریون; Prion protein; Transmembrane domain; Membrane topology; α-Cleavage; C1 fragmentα1-3, α-helical structure; β1-2, β-sheet structure; aa, aminoacids; Ab, antibody; ADAM, A disintegrin and metalloproteinase; AP, acceptor peptide; APP, amyloid precursor protei
ImmunoAT method: An initial assessment for the detection of abnormal isoforms of prion protein in formalin-fixed and paraffin-embedded tissues
Keywords: پروتئین پریون; ImmunoAT method; AT-tailing; Immunohistochemistry; Prion protein; Bovine spongiform encephalopathy
Nickel(II) complexes of the multihistidine peptide fragments of human prion protein
Keywords: پروتئین پریون; Prion protein; Peptides; Nickel(II); Stability constants; Histidine; Circular dichroism
Characterization of discontinuous epitope of prion protein recognized by the monoclonal antibody T2
Keywords: پروتئین پریون; Prion protein; Antibody; Epitope; Conformation; Intramolecular interactions
A novel copper(II) coordination at His186 in full-length murine prion protein
Keywords: پروتئین پریون; Prion protein; Cu(II); C-terminal domain; ESR; SDSL; MTSSL; Interspin distance; Dipolar interaction; Histidine residue