Mutated MITF-E87R in Melanoma Enhances Tumor Progression via S100A4
Keywords: siRNA; ChIP; chromatin immunoprecipitation; siRNA; small interfering RNA; WT; wild type;
مقالات ISI siRNA (ترجمه نشده)
مقالات زیر هنوز به فارسی ترجمه نشده اند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
در صورتی که به ترجمه آماده هر یک از مقالات زیر نیاز داشته باشید، می توانید سفارش دهید تا مترجمان با تجربه این مجموعه در اسرع وقت آن را برای شما ترجمه نمایند.
Can we increase the speed and efficacy of antidepressant treatments? Part II. Glutamatergic and RNA interference strategies
Keywords: siRNA; Ketamine; microRNA; Prefrontal cortex; Small interfering RNA; RNA interference; 5-HT; serotonin; 5-HT1A receptor; serotonin 1A receptor; A1; adenosine A1 receptor; AchE; acetylcholinesterase; AGO; argonaute; Akt-mTOR; protein kinase B/Akt- mammalian targe
Umbilical cord-derived mesenchymal stem cells alleviated inflammation and inhibited apoptosis in interstitial cystitis via AKT/mTOR signaling pathway
Keywords: siRNA; Stem cells; Cystitis; Inflammation; Apoptosis; IC; interstitial cystitis; UC-MSCs; umbilical cord-derived mesenchymal stem cells; CYP; cyclophosphamide; siRNA; small interfering RNA; EGF; epidermal growth factor;
IL-1/inhibitory κB kinase ε-induced glycolysis augment epithelial effector function and promote allergic airways disease
Keywords: siRNA; Asthma; house dust mite; glycolysis; IL-1; inhibitor of κB kinase ε; lactate; lactate dehydrogenase A; AHR; Airways hyperresponsiveness; BAL; Bronchoalveolar lavage; BMI; Body mass index; DC; Dendritic cell; 2-DG; 2-Deoxyglucose; ECAR; Extracellular aci
The role and mechanism of KCa3.1 channels in human monocyte migration induced by palmitic acid
Keywords: siRNA; BSA; bovine serum albumin; ELISA; enzyme linked immunosorbent assay; FBS; fetal bovine serum; FFAs; free fatty acids; HUVECs; human umbilical vein endothelial cells; MCP-1; monocyte chemoattractant protein-1; NF-κB; nuclear factor-κB; PA; palmitic acid;
Activation of the STING-IRF3 pathway promotes hepatocyte inflammation, apoptosis and induces metabolic disorders in nonalcoholic fatty liver disease
Keywords: siRNA; ALT; Alanine aminotransferase; AST; Aspartate aminotransferase; AUC; Area under the curve; BW; body weight; DMEM; Dulbecco's modified Eagle's medium; ER; endoplasmic-reticulum; FBS; fetal bovine serum; FFA; free fatty acid; GCK; glucokinase; p-GSK3β; pho
Conserved association of Argonaute 1 and 2 proteins with miRNA and siRNA pathways throughout insect evolution, from cockroaches to flies
Keywords: siRNA; Argonaute proteins; RNAi; miRNA; siRNA; Blattella; Drosophila;
Injectable and protease-degradable hydrogel for siRNA sequestration and triggered delivery to the heart
Keywords: siRNA; siRNA; Myocardial infarction; Hydrogel; Matrix metalloprotease;
Increased Neuroligin 2 Levels in the Postsynaptic Membrane in Spinal Dorsal Horn may Contribute to Postoperative Pain
Keywords: siRNA; AMPA; α-amino-3-hydroxy-5-methyl-4-isoxazole propionate; CPS; cumulative pain score; PSD-95; postsynaptic density protein 95; PWT; paw withdrawal threshold; siRNA; small interfering ribonucleic acid; TTBS; Tween/Tris-buffered saline solution; postoperati
Aptamer-guided siRNA-loaded nanomedicines for systemic gene silencing in CD-44 expressing murine triple-negative breast cancer model
Keywords: siRNA; Liposomes; siRNA; Protamine; Aptamers; Cancer stem cell; CD44;
Hepatic-targeted RNA interference provides robust and persistent knockdown of alpha-1 antitrypsin levels in ZZ patients
Keywords: siRNA; siRNA; Phase 1; PiZZ; RNAi; Therapeutic;
The proteoglycan biglycan mediates inflammatory response by activating TLR-4 in human chondrocytes: Inhibition by specific siRNA and high polymerized Hyaluronan
Keywords: siRNA; Biglycan; Hyaluronan; NF-kB; TLR-4; Cytokines; Inflammation; Chondrocytes; siRNA;
IsomiR processing during differentiation of myelogenous leukemic cell line K562 by phorbol ester PMA
Keywords: siRNA; CML; chronic myelogenous leukemia; PMA; phorbol 12-myristate 13-acetate; NGS; next generation sequencing; TPM; trimmed per million; %; percentage; NET1; neuro-epithelial transforming gene 1; YARS; tyrosyl-tRNA synthetase; IPO7; importin 7; MTHFR; methylen
Synthesis of cationic branched tea polysaccharide derivatives for targeted delivery of siRNA to hepatocytes
Keywords: siRNA; Tea polysaccharide; Hepatocytes; Glycometabolism enzyme; siRNA; Gene delivery;
Chitosan (CMD)-mediated co-delivery of SN38 and Snail-specific siRNA as a useful anticancer approach against prostate cancer
Keywords: siRNA; Chitosan; SN38; Snail; siRNA; Nanoparticle; Prostate cancer;
Development of siRNA mediated RNA interference and functional analysis of novel parasitic nematode-specific protein of Setaria digitata
Keywords: siRNA; Setaria digitata; siRNA; RNAi; SDNP;
Suppression of p53R2 gene expression with specific siRNA sensitizes HepG2 cells to doxorubicin
Keywords: siRNA; dNTP; deoxynucleotide; HHC; hepatocellular carcinoma; PI; propidium iodide; qRT-PCR; quantitative real-time PCR; p53R2; siRNA; Doxorubicin; Chemotherapy; HepG2;
Signaling pathways involved in the rapid biphasic effect of aldosterone on Na+/H+ exchanger in rat proximal tubule cells
Keywords: siRNA; Aldo; Aldosterone; MR; mineralocorticoid receptor; GR; glucocorticoid receptor; pHi; intracellular pH; pHirr; intracellular pH recovery rate; NHE1; basolateral Na+/H+ exchanger isoform 1; [Ca2+]i; cytosolic free calcium concentration; PLC; phospholipase C
Reduced retromer function results in the accumulation of amyloid-beta oligomers
Keywords: siRNA; AF700; AlexaFluor-700; AD; Alzheimer's disease; Aβ; Amyloid beta; oAβ; Amyloid beta oligomers; APP; Amyloid precursor protein; BACE1; Beta-secretase 1; BDNF; Brain-derived neurotrophic factor; cDNA; Complementary DNA; CSF; Cerebrospinal fluid; EEA1; Ear
NRAGE confers poor prognosis and promotes proliferation, invasion, and chemoresistance in gastric cancer
Keywords: siRNA; NRAGE; neurotrophin receptor-interacting melanoma antigen-encoding protein; UICC; Union for International Cancer Control; OS; overall survival; siRNA; small interfering RNA; p-ERK; phospho-extracellular regulated protein kinase; ZO-1; zonula occludens-1;
FKBP8 protects the heart from hemodynamic stress by preventing the accumulation of misfolded proteins and endoplasmic reticulum-associated apoptosis in mice
Keywords: siRNA; αMHC-Cre; α-myosin heavy chain promoter-driven Cre recombinase; BCL2L13; Bcl-2-like protein 13; CCCP; mitochondrial uncoupler carbonyl cyanide m-chlorophenylhydrazone; ER; endoplasmic reticulum; FKBP8; FK506-binding protein 8; GRP78; glucose-regulated p
Glyco-Mapper: A Chinese hamster ovary (CHO) genome-specific glycosylation prediction tool
Keywords: siRNA; CCM; central carbon metabolism; CHO; Chinese hamster ovary; DReaM-zyP; Discretized Reaction Network Modeling using Fuzzy Parameters; EPO; erythropoietin; mAb; monoclonal antibody; SEAP; secreted alkaline phosphatase; siRNA; short interfering RNA; Chinese
Functions of the Vasa gene in Schistosoma japonicum as assessed by RNA interference
Keywords: siRNA; S. japonicum; Schistosoma japonicum; SjVasa3; Schistosoma japonicum Vasa3; siRNA; small interfering siRNA; qPCR; quantitative PCR; RNAi; RNA interference; TBST; Tris-Buffered Saline and Tween 20; CLSM; confocal laser scanning microscopy; Schistosoma japon
Lysine demethylase inhibition protects pancreatic β cells from apoptosis and improves β-cell function
Keywords: siRNA; Apoptosis; β cells; Inflammation; Lysine demethylases; Gene expression; Diabetes; ATF; Activating transcription factor; ChIP; Chromatin immunoprecipitation; CHOP; C/EBP homologous protein; DP; Death promoting gene; ER; Endoplasmic reticulum; FDH; Formald
Development of a peptide-modified siRNA nanocomplex for hepatic stellate cells
Keywords: siRNA; Liver fibrosis; siRNA; Nanocomplex; IGF2R; Phage; Peptide ligand; Vitamin A;
The longevity gene INDY (I'm Not Dead Yet) in metabolic control: Potential as pharmacological target
Keywords: siRNA; Aak2; 5â²AMP-activated protein kinase catalytic subunit alpha-2; ACC; acetyl CoA carboxylase; Acly; ATP citrate lyase; Adipo-IR; adipose tissue insulin resistance index; ADME; absorption, distribution, metabolism, excretion; AGA; appropriate-for-gestatio
Ruthenium dendrimers as carriers for anticancer siRNA
Keywords: siRNA; Dendrimer; Ruthenium; siRNA; Drug delivery; Computer modeling; Molecular dynamics;
Opposing Roles of Epidermal Integrins α3β1 and α9β1 in Regulation of mTLD/BMP-1-Mediated Laminin-γ2 Processing during Wound Healing
Keywords: siRNA; α3eKO; integrin α3 epidermal knockout; α9eKO; integrin α9 epidermal knockout; α3/α9eKO; integrin α3/α9 double epidermal knockout; BM; basement membrane; ECM; extracellular matrix; LN; laminin; LNγ2; laminin-γ2; MK; mouse keratinocyte; siRNA; sma
Regulation and function of runt-related transcription factors (RUNX1 and RUNX2) in goat granulosa cells
Keywords: siRNA; RUNX1; runt-related transcription factor 1; RUNX2; runt-related transcription factor 2; hCG; human chorionic gonadotropin; LH; Luteinizing Hormone; FSK; forskolin; PMA; phorbol 12-myristate 13-acetate; PI3K; phosphatidylinositol 3 kinase; PKA; protein kin
Testin and filamin-C downregulation by acetylated Siah2 increases invasiveness of Helicobacter pylori-infected gastric cancer cells
Keywords: siRNA; ac-lys; acetylated lysine; ac-Siah2; acetylated Siah2; ac-K139 Siah2; acetylated K139 Siah2; ASB2; a suppressor of cytokine signalling box 2 gene; cag; cytotoxin-associated gene; CHIP; C-terminus of Hsc70 interacting protein; DAPI; 4',6-Diamidino-2-phenyl
Exosome-mediated miR-222 transferring: An insight into NF-κB-mediated breast cancer metastasis
Keywords: siRNA; BCa; Breast Cancer; TNBCa; Triple-negative BCa; miRNA; MicroRNA; siRNA; Small interfering RNA; ER; Estrogen receptor; NF-κB; Nuclear factor-κb; PDLIM2; PDZ and LIM domain protein 2; qRT-PCR; Quantitative reverse transcription-PCR; TEM; Transmission elec
Therapeutic applications of zebrafish (Danio rerio) miRNAs linked with human diseases: A prospective review
Keywords: siRNA; miRNA; Micro RNA; RNA; Ribonucleic acid; RNase III; Ribonuclease III; mRNA; Messenger RNA; RISC; RNA-induced silencing complex; UTR; Untranslated region; Pre-miRNA; Precursor micro RNA; DGCR8; Digeorge syndrome chromosomal [or critical] region 8; TRBP; Tr
MicroRNA-155 induces autophagy in osteoclasts by targeting transforming growth factor β-activated kinase 1-binding protein 2 upon lipopolysaccharide stimulation
Keywords: siRNA; BMM; bone marrow-derived macrophages; M-CSF; macrophage-colony stimulating factor; miR; microRNA; miR-155; microRNA-155; MNC; multinucleated cells; OC; osteoclast; PBS; phosphate-buffered saline; qPCR; quantitative polymerase chain reaction; RANKL; recept
Expression and therapeutic implications of cyclin-dependent kinase 4 (CDK4) in osteosarcoma
Keywords: siRNA; CDK4; cyclin-dependent kinase 4; RNAi; RNA interference; siRNA; small interfering RNA; Rb; retinoblastoma; TMA; tissues microarray; Osteosarcoma; Cyclin-dependent kinase 4; Palbociclib; Rb; Cell cycle;
KLF15 promotes transcription of KLF3 gene in bovine adipocytes
Keywords: siRNA; KLF; Krüppel-like factors; EMSA; Electrophoretic mobility shift; ChIP; Chromatin immunoprecipitation; IMF; Intramuscular fat content; PPARγ; Peroxisome proliferator-activated receptor; GLUT4; glucose transport protein; EAMC; Committee of Experimental An
Epigenetics of breast cancer: Biology and clinical implication in the era of precision medicine
Keywords: siRNA; BC; breast Cancer; ER; estrogen Receptor; PgR,PR; progesteron receptor; HER-2; human epidermal growth factor receptor 2; TNBC; triple negative breast cancer; ncRNA; non coding RNA; CpG(s); cytosine-phosphate-guanine dinucleotide(s); 5-me-C; 5-methyl-cytos
Curcumin enhances LXRα in an AMP-activated protein kinase-dependent manner in human macrophages
Keywords: siRNA; LXR; liver X receptor; ABCA1; ATP-binding cassette transporter A1; ABCG1; ATP-binding cassette transporter G1; SREBP1c; sterol response element binding protein 1c; AMPK; AMP-activated protein kinase; PMA; phorbol myristate acetate; fMLP; formyl-Met-Leu-Ph
TGF-β1 acts as mediator in fluoride-induced autophagy in the mouse osteoblast cells
Keywords: siRNA; Autophagy; Fluoride; Mouse osteoblast cell; Proliferation; TGF-β1; ANOVA; one-way analysis of variant; Atg; autophagy-related; BCA; Bicinchoninic Acid; DAPI; 4â²,6-diamidino-2-phenylindole; DMEM/F12; Dulbecco's Modified Eagle Medium/F12; ECL; Electro-Ch
Efficient EFGR mediated siRNA delivery to breast cancer cells by Cetuximab functionalized Pluronic® F127/Gelatin
Keywords: siRNA; Polymeric micelles; siRNA; AKT2; Cetuximab; Pluronic® F127; Gelatin; Breast cancer;
MiR-31 Mediates Inflammatory Signaling to Promote Re-Epithelialization during Skin Wound Healing
Keywords: siRNA; 3â²-UTR; 3â²-untranslated region; Ccnd1; Cyclin D1; cKO; conditional knockout; MAPK; mitogen-activated protein kinase; PWD; post wounding; siRNA; small interfering RNA; STAT3; signal transducer and activator of transcription 3; TNF-α; tumor necrosis fa
CCN1/Cyr61 Stimulates Melanogenesis through Integrin α6β1, p38 MAPK, and ERK1/2 Signaling Pathways in Human Epidermal Melanocytes
Keywords: siRNA; NHEK; normal human epidermal keratinocyte; NHEM; normal human epidermal melanocyte; siRNA; small interfering RNA;
Association Between Germline Mutations in BRF1, a Subunit of the RNA Polymerase III Transcription Complex, and Hereditary Colorectal Cancer
Keywords: siRNA; Colon Cancer; Familial Colorectal Cancer; Protein Translation; Mechanism; CRC; colorectal cancer; LOH; loss of heterozygosity; MAF; minor allele frequency; miRNA; microRNA; MMR; DNA mismatch repair; PBS; phosphate-buffered saline; PCR; polymerase chain re
Role of p-MKK7 in myricetin-induced protection against intestinal ischemia/reperfusion injury
Keywords: siRNA; 5281672; I/R; ischemia/reperfusion; H/R; hypoxia/reoxygenation; SMA; superior mesenteric artery; IEC-6; Intestinal epithelial cells; TNF-α; tumor necrosis factor alpha; IL-1β; interleukin-1β; IL-6; interleukin-6; MDA; malondialdehyde; SOD; superoxide d
Targeted-gene silencing of BRAF to interrupt BRAF/MEK/ERK pathway synergized photothermal therapeutics for melanoma using a novel FA-GNR-siBRAF nanosystem
Keywords: siRNA; GNR; gold nanorods; siRNA; small interfering RNA; siBRAF; siRNA specific for BRAF; FA; folic acid; CTAB; cetyltrimethylammonium bromide; MUA; mercaptoundecanoic acid; PEI; polyethylene imine; TEM; transmission electron microscope; NMR; nuclear magnetic re
Lipidation of polyethylenimine-based polyplex increases serum stability of bioengineered RNAi agents and offers more consistent tumoral gene knockdown in vivo
Keywords: siRNA; Bioengineering; RNA delivery; Lipopolyplex; siRNA; Cancer; Orthotopic HCC; Mouse model;
CISD2 inhibition overcomes resistance to sulfasalazine-induced ferroptotic cell death in head and neck cancer
Keywords: siRNA; Cancer resistance; Ferroptosis; Nutrient-deprivation autophagy factor-1; System xc-cystine/glutamate antiporter; Pioglitazone; CISD; CDGSH iron sulfur domain; ER; endoplasmic reticulum; FTH1; ferritin heavy chain 1; GPX4; glutathione peroxidase 4; GSH; gl
Phosphorylation of Mig6 negatively regulates the ubiquitination and degradation of EGFR mutants in lung adenocarcinoma cell lines
Keywords: siRNA; Mig6; Mitogen-inducible gene 6; EGF; epidermal growth factor; EGFR; epidermal growth factor receptor; RTK; Receptor tyrosine kinase; WT; Wild type; 19del; EGFR (del E746-A750); L858R; EGFR substitution of leucine to arginine residue 858; SILAC; stable i
BCAP promotes osteoclast differentiation through regulation of the p38-dependent CREB signaling pathway
Keywords: siRNA; BCAP; B-cell adaptor for PI3K; PI3K; phosphatidylinositol 3-Kinase; BMM; bone marrow-derived monocyte/macrophage lineage cell; NFATc1; nuclear factor of activated T-cells c1; TRAP; tartrate-resistant acid phosphatase; RANKL; receptor activator of nuclear
The Tumor-Promoting Role of TRIP4 in Melanoma Progression and its Involvement in Response to BRAF-Targeted Therapy
Keywords: siRNA; HAT; histone acetyltransferase; LPS; lipopolysaccharide; siRNA; small interfering RNA;
Angiotensin II facilitates neointimal formation by increasing vascular smooth muscle cell migration: Involvement of APE/Ref-1-mediated overexpression of sphingosine-1-phosphate receptor 1
Keywords: siRNA; Angiotensin II; Vascular smooth muscle cell (VSMC); Sphingosine-1-phosphate receptor (S1PR); APE/Ref-1; Vascular neointima; DCF-DA; 6-carboxy-2â²,7â²-dichlorofluoroscein diacetate; Ang II; angiotensin II; AT; Ang II receptor; APE/Ref-1; apurinic/apyrimi